Is metastatic squamous cell carcinoma curable?
Squamous cell carcinoma (SCC) generally has a high survival rate. The 5-year survival is 99 percent when detected early. Once SCC has spread to the lymph nodes and beyond, the survival rates are lower. Yet this cancer is still treatable with surgery and other therapies, even in its advanced stages.
How long can you live with metastatic squamous cell carcinoma?
SCC metastasis is generally associated with a poor prognosis with a 3-year disease-free survival rate in adult patients of 56% (3). Relapse of SCC is common, with the cumulative relapse rate ~29% within 1-year of treatment.
Is squamous cell carcinoma highly metastatic?
Metastasis of cutaneous squamous cell carcinoma (cSCC) is rare. However, certain tumor and patient characteristics increase the risk of metastasis. Prior studies have demonstrated metastasis rates of 3-9%, occurring, on average, one to two years after initial diagnosis .
How do I know if my squamous cell carcinoma has metastasized?
Your doctor will look at the results of the biopsy to determine the stage. If you have squamous cell skin cancer, your doctor may also recommend imaging such as CT or PET-CT scan, or testing lymph nodes near the tumor to see if the cancer has spread beyond the skin.
What is the prognosis of squamous cell carcinoma?
In general, the squamous cell carcinoma survival rate is very high—when detected early, the five-year survival rate is 99 percent. Even if squamous cell carcinoma has spread to nearby lymph nodes, the cancer may be effectively treated through a combination of surgery and radiation treatment.
Does squamous cell carcinoma spread fast?
Squamous cell carcinoma rarely metastasizes (spreads to other areas of the body), and when spreading does occur, it typically happens slowly. Indeed, most squamous cell carcinoma cases are diagnosed before the cancer has progressed beyond the upper layer of skin.
Where does squamous cell carcinoma usually metastasize to?
Cancer can begin in squamous cells anywhere in the body and metastasize (spread) through the blood or lymph system to other parts of the body. When squamous cell cancer spreads to lymph nodes in the neck or around the collarbone, it is called metastatic squamous neck cancer.
What is aggressive squamous cell carcinoma?
What is aggressive squamous cell carcinoma? “Aggressive SCC” or “high-risk SCC” is cancer that is more likely to recur (return after initial treatment) or metastasize (spread to other parts of the body). Features of high-risk SCC are: Larger than 2 centimeters (cm)
Why does squamous cell carcinoma keep coming back?
That’s because individuals who were diagnosed and treated for a squamous cell skin lesion have an increased risk of developing a second lesion in the same location or a nearby skin area. Most recurrent lesions develop within two years after the completion of treatment to remove or destroy the initial cancer.
Should I worry about squamous cell carcinoma?
Squamous cell carcinoma of the skin is usually not life-threatening, though it can be aggressive. Untreated, squamous cell carcinoma of the skin can grow large or spread to other parts of your body, causing serious complications.
What is Stage 2 squamous cell carcinoma?
Stage 2 squamous cell carcinoma: The cancer is larger than 2 centimeters across, and has not spread to nearby organs or lymph nodes, or a tumor of any size with 2 or more high risk features.
What organs does squamous cell carcinoma affect?
Squamous cell carcinoma can spread to other parts of the body, including fatty tissues, lymph nodes, and internal organs. It can cause death. Squamous cell carcinomas located on the lip, ears, palm of the hand, or sole of the foot have the highest risk of spreading.