How long do you live with transitional cell carcinoma?
Overall survival and cancer-specific survival
For the entire cohort, there were 986 (51.6%) patients who died and 704 (36.9%) patients who died from primary transitional cell carcinoma of the ureter. The median overall survival (OS) was 46 months, and the 5-year OS rate was 41.8%.
Is transitional cell carcinoma fatal?
Renal UC is uniformly fatal unless it is treated. In a multicenter study of 1363 patients with upper urinary tract urothelial carcinoma who were treated with radical nephroureterectomy, the 5-year cancer-specific survival probability was approximately 73%.
How aggressive is transitional cell carcinoma?
Transitional Cell Carcinoma: An Aggressive Cancer. Transitional cell carcinoma affects the transitional cells of the urinary system and accounts for an overwhelming majority of bladder cancer diagnoses. This cancer may spread rapidly, affecting other organs and becoming life-threatening in some cases.
How serious is transitional cell carcinoma?
If it’s high grade, it’s more likely to spread to deeper layers of your bladder, other areas of your body, and your lymph nodes. It’s also likely to come back after treatment. High-grade TCC is the type of bladder cancer that is more likely to be life-threatening.
What is the primary symptom of transitional cell carcinoma?
The symptoms of transitional cell cancer of the kidney are similar to those of other types of kidney cancer. They include blood in the urine and pain in your back, between the lower ribs, and the top of your hip bone. You may also need to pass urine very often or have pain when passing urine.
Where does TCC metastasis to?
Transitional cell carcinoma (TCC) of the bladder commonly metastasizes to the pelvic lymph nodes, lungs, liver, bones, adrenals, or brain. Unusual sites include the heart, kidney, spleen, pancreas, and reproductive system.
Can a cancerous ureter be replaced?
Surgery is often recommended to remove ureteral cancer. The extent of your surgery will depend on your situation. For very early-stage ureteral cancer, surgery may involve removing only a portion of the ureter.
What is upper tract transitional cell carcinoma?
Upper urinary tract transitional cell carcinoma (TCC) refers to malignant changes of the transitional epithelial cells lining the urinary tract from the renal calyces to the ureteral orifice.