When do you give G-CSF?
G-CSF is approved by the United States Food and Drug Administration (FDA) for use to decrease the incidence of infection in patients with non-myeloid malignancies receiving myelosuppressive anti-cancer drugs associated with a significant incidence of severe neutropenia with fever; reduce the time to neutrophil recovery …
Why is G-CSF given 24 hours after chemo?
Post-chemotherapy prophylactic granulocyte colony-stimulating factor (G-CSF) is customarily started 24 hours after chemotherapy in most of the current pediatric and adult solid tumors protocols to ameliorate the myelotoxicity of cytotoxic agents and reduce neutropenia-related complications.
When should I take filgrastim injection after chemo?
The manufacturer recommends that the first dose of filgrastim be given no sooner than 24 hours after chemotherapy. Your doctor will discontinue therapy with filgrastim when your white blood cell count has reached acceptable levels.
When is Neupogen given after chemo?
Administer the first dose of NEUPOGEN at least 24 hours after cytotoxic chemotherapy and at least 24 hours after bone marrow infusion.
How quickly does G-CSF work?
This usually takes 5 to 7 days, although it can be longer. Long-acting G-CSF is given as a single injection the day after chemotherapy has completed. If you are having G-CSF before a stem cell transplant, you usually have your first injection 4 to 6 days before your stem cells are going to be collected.
What are the injections after chemo?
CSFs include Neupogen (filgrastim), Neulasta (pegfilgrastim), and Leukine and Prokine (sargramostim). They are usually given as shots 24 hours after a chemotherapy treatment.
When is the best time to inject filgrastim?
The first filgrastim injection is usually given on the fourth day of your chemotherapy cycle for a total of seven days. Some chemotherapy treatments might require you to administer the filgrastim syringes on a different day.
Does G-CSF increase platelet count?
Primarily, G-CSF stimulates the bone marrow to produce granulocytes and stem cells. A decreased platelet count was occasionally observed after G-CSF injection. A previous study indicated that G-CSF also increases platelet turnover and loss.
How can I increase my white blood cells after chemo?
The only treatment that has been proved to increase the number of white blood cells after chemotherapy is an injectable medicine that stimulates the bone marrow to make white blood cells faster.
Does filgrastim have to be given at the same time each day?
To help you remember, use it at the same time each day. If you are receiving cancer chemotherapy, you should not use this medication within 24 hours before or 24 hours after chemotherapy.
How long does bone pain last after filgrastim?
Bone pain caused by Neulasta lasts at least 8 days for 49% of the patients, and most likely longer for a large number of patients.