What do cancer margins mean?

Does clear margins mean cancer free?

A clear, negative, or clean margin means there are no cancer cells at the outer edge of tissue that was removed. A positive margin means that cancer cells come right out to the edge of the removed tissue and have ink on them.

What does positive margins mean on a biopsy?

Another important factor is whether there are cancer cells at the margins, or edges, of the biopsy sample. A “positive” or “involved” margin means there are cancer cells in the margin. This means that it is likely that cancerous cells are still in the body.

What does it mean when margins are not clear?

Negative (also called clean, not involved or clear) margins

The margins do not contain cancer cells. (There’s only normal tissue at the edges of the tissue removed from the breast.) In most cases, no more surgery is needed.

Does Stage 1 cancer require chemo?

Chemotherapy is usually not part of the treatment regimen for earlier stages of cancer. Stage 1 is highly treatable, however, it does require treatment, typically surgery and often radiation, or a combination of the two.

Are biopsies 100% accurate?

Although tests aren’t 100% accurate all the time, receiving a wrong answer from a cancer biopsy – called a false positive or a false negative – can be especially distressing. While data are limited, an incorrect biopsy result generally is thought to occur in 1 to 2% of surgical pathology cases.

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What is positive margin?

The margin is described as positive or involved when the pathologist finds cancer cells at the edge of the tissue, suggesting that all of the cancer has not been removed.

Can a surgeon tell if a tumor is cancerous by looking at it?

Cancer is nearly always diagnosed by an expert who has looked at cell or tissue samples under a microscope. In some cases, tests done on the cells’ proteins, DNA, and RNA can help tell doctors if there’s cancer. These test results are very important when choosing the best treatment options.

What is a negative profit margin?

Gross profit margin can turn negative when the costs of production exceed total sales. A negative margin can be an indication of a company’s inability to control costs. … Gross profit is the revenue earned by a company after deducting the direct costs of producing its products.

Do you always have to have radiation after a lumpectomy?

Will I need radiation therapy if I have a lumpectomy? Yes, radiation therapy is almost always recommended after lumpectomy. Cancer can return in the same breast after surgery (local recurrence). Studies have shown that radiation therapy significantly reduces the risk of local recurrence.