Does high AFP mean cancer?
Increased AFP levels may indicate the presence of cancer, most commonly liver cancer, cancer of the ovary, or germ cell tumor of the testicles. However, not every liver, ovarian, or testicular cancer will produce significant quantities of AFP.
Is AFP genetic?
GeneCards Summary for AFP Gene
AFP (Alpha Fetoprotein) is a Protein Coding gene. Diseases associated with AFP include Alpha-Fetoprotein Deficiency and Alpha-Fetoprotein, Hereditary Persistence Of.
Is AFP a tumor marker?
AFP is 1 of several tumor markers. Tumor markers are molecules in the blood that are higher when a person has certain cancers. AFP is found mainly in liver cancer and germ cell tumors of the testicles or ovaries, which are rare.
How accurate is AFP test for cancer?
The sensitivity and specificity of AFP >20 ng/mL for the detection of HCC were 70.1% and 89.8%, respectively.
What is an abnormal AFP result?
What do the results mean? If your results show higher than normal AFP levels, it may mean your baby has a neural tube defect such as spina bifida, a condition in which the bones of the spine don’t close around the spinal cord, or anencephaly, a condition in which the brain does not develop properly.
What happens if an AFP test is positive?
What does it mean if my AFP PLUS test result is screen positive? A positive AFP PLUS test means that you are in a higher likelihood group for having a baby with a neural tube defect or a chromosome abnormality. However, it does not prove by itself that there is anything wrong with the pregnancy.
What does AFP indicate?
AFP stands for alpha-fetoprotein. It is a protein made in the liver of a developing baby. AFP levels are usually high when a baby is born, but fall to very low levels by the age of 1. Healthy adults should have very low levels of AFP. An AFP tumor marker test is a blood test that measures the levels of AFP in adults.
Does AFP testing tell gender?
Non-Invasive Prenatal Screening
It does screen for an increase in chromosomes 21, 18, and 13. It also can detect the gender of baby. It does not screen for all chromosomes.
Why is AFP low in Down syndrome?
Causes of this decrease may include the production of an altered AFP molecule with modified turnover or transport properties, or a reduction in the level of AFP synthesis.
What is normal tumor marker level?
Normal range: < 2.5 ng/ml. Normal range may vary somewhat depending on the brand of assay used. Levels > 10 ng/ml suggest extensive disease and levels > 20 ng/ml suggest metastatic disease.
How do you control AFP levels?
Iron reduction therapy significantly reduced the median level of serum AFP from 13 to 7 ng/mL, ALT from 96 to 50 IU/L, gamma-glutamyl transpeptidase (GGT) from 55 to 28 IU/L, and ferritin from 191 to 10 ng/mL ( for each).