What drug class is Xtandi?
This medication belongs to a class of drugs known as anti-androgens (anti-testosterone). It works by blocking the effects of testosterone to slow the growth and spread of prostate cancer.
What kind of treatment is Xtandi?
XTANDI is a prescription medicine used to treat men with prostate cancer that no longer responds to a hormone therapy or surgical treatment to lower testosterone OR has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone.
How long can you stay on Xtandi?
How long does Xtandi extend life? In the AFFIRM trial, treatment with Xtandi extended life by almost 5 months. Treatment with Xtandi resulted in a median overall survival time of 18.4 months (95% CI 17.3 to not yet reached) compared with 13.6 months (95% CI 11.3 to 15.8) in the placebo recipients (p<0.001).
Can Xtandi cure cancer?
Xtandi is approved to treat prostate cancer that’s castration resistant. This type of cancer no longer improves with typical medications or surgical treatments that work to lower testosterone levels. Other drugs are available that can treat this condition.
How much is Xtandi a month?
The total cost for a one-month supply of Xtandi (120 pills) as listed on in the “Explanation of Benefits” document comes out to $8,839.49, or around $73.66 per pill, $294.64 per day, and $107,617.26 per year. This is the reduced price for medicare patients.
What happens when you stop taking Xtandi?
If your doctor thinks Xtandi has stopped working they will advise you to stop taking it. In about 50 percent of the men whose PSA level starts to rise again while on antiandrogen therapy, stopping treatment will lead to antiandrogen withdrawal syndrome or antiandrogen withdrawal response (AAWR).
Can you drink alcohol with enzalutamide?
The drinking of alcohol may increase your risk of certain side effects (seizures). Discuss with your doctor before being treated with enzalutamide. Enzalutamide may damage sperm and may harm the baby if used during pregnancy.
Does xtandi cause hair loss?
Xtandi targets multiple steps in the androgen-receptor–signaling pathway, interfering with molecular pathways that help the cancer grow. What’s more, the drug does not cause side effects commonly associated with chemotherapy, such as nausea and hair loss.
Which is better xtandi vs Zytiga?
The use of enzalutamide (XTANDI) to treat men with chemotherapy-naÃ¯ve metastatic castrate-resistant prostate cancer (mCRPC) is associated with better overall survival and significantly lower resource use and health care costs compared with abiraterone acetate (ZYTIGA), according to findings from a retrospective …
When should I stop taking Xtandi?
If you want to stop taking Xtandi (enzalutamide), a prescription medication used to treat metastatic castration-resistant prostate cancer, first talk to your doctor. Your doctor may tell you to stop taking Xtandi if you have severe side effects, such as seizures.
How good is Xtandi?
Xtandi has an average rating of 4.1 out of 10 from a total of 10 ratings for the treatment of Prostate Cancer. 30% of reviewers reported a positive effect, while 60% reported a negative effect.
When should you take Xtandi?
XTANDI is taken by mouth and is available in 2 dosage strengths: 40 mg and 80 mg. Take XTANDI once a day, at the same time every day, with or without food.