Does chemotherapy cure melanoma?
Although chemo won’t cure melanoma, it can relieve symptoms and it may help you live longer. It sometimes works better when you also take immunotherapy drugs. If your cancer is only in your arm or leg, you may get chemotherapy in just that limb. Doctors call this treatment “isolated limb perfusion.”
What percentage of melanoma patients respond to chemotherapy?
Although surgery and radiation therapy have a role in the treatment of metastatic disease, systemic therapy is the mainstay of treatment for most patients. Single-agent chemotherapy is well tolerated but is associated with response rates of only 5% to 20%.
Is melanoma resistant to chemotherapy?
Melanoma is a most dangerous and deadly type of skin cancer, and considered intrinsically resistant to both radiotherapy and chemotherapy.
What is the most effective treatment for melanoma?
The main treatment for melanoma is surgical removal, or excision, of the primary melanoma on the skin. The extent of the surgery depends on the thickness of the melanoma. Most melanomas are found when they are less than 1.0 mm thick, and outpatient surgery is often the only treatment needed.
Where does melanoma usually spread to first?
Normally, the first place a melanoma tumor metastasizes to is the lymph nodes, by literally draining melanoma cells into the lymphatic fluid, which carries the melanoma cells through the lymphatic channels to the nearest lymph node basin.
Can melanoma be completely cured?
Treatment can completely cure melanoma in many cases, especially when it has not spread extensively. However, melanoma can also recur. It is natural to have questions about the treatment, its side effects, and the chances of cancer recurring.
How long does it take melanoma to spread?
Melanoma can grow very quickly. It can become life-threatening in as little as six weeks and, if untreated, it can spread to other parts of the body. Melanoma can appear on skin not normally exposed to the sun.
Why is melanoma chemo resistant?
Researchers have identified a major reason why melanoma is largely resistant to chemotherapy. They found a genetic pathway in melanoma cells that inhibits the cellular mechanism for detecting DNA damage wrought by chemotherapy, thereby building up tolerance to cancer-killing drugs.