How long is docetaxel effective?
The median overall survival (OS) was 81 months with docetaxel plus standard of care (hormonal therapy with or without radiotherapy) versus 71 months with standard of care alone (0.78; 95% CI, 0.66-0·93;P= . 006).
Does docetaxel shrink tumors?
Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as docetaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
How effective is docetaxel?
Doses of 100 mg/m2 of docetaxel, administered over 1 hour every 3 weeks, produced an overall response rate of 50% (range, 41% to 58%) in 129 evaluable patients, with a median duration of 6 months (range, 2 to 17 months).
How many times can you have docetaxel?
How long will I have docetaxel for? For primary breast cancer three to six treatment cycles are usually given. For locally advanced and secondary breast cancer the number of cycles will vary depending on the individual.
What is the most common side effect of docetaxel?
The most common adverse reactions across all TAXOTERE indications are infections, neutropenia, anemia, febrile neutropenia, hypersensitivity, thrombocytopenia, neuropathy, dysgeusia, dyspnea, constipation, anorexia, nail disorders, fluid retention, asthenia, pain, nausea, diarrhea, vomiting, mucositis, alopecia, skin …
Is cabazitaxel stronger than docetaxel?
The phase III FIRSTANA trial has shown no difference in overall survival with two dose regimens of cabazitaxel (Jevtana) vs docetaxel in the first-line treatment of metastatic castration-resistant prostate cancer. Results were reported by Oudard et al in the Journal of Clinical Oncology.
How much does docetaxel cost?
The cost for docetaxel intravenous solution (20 mg/mL) is around $28 for a supply of 1 milliliter(s), depending on the pharmacy you visit.
|2 milliliters||$23.23 – $137.59||$46.46 – $275.18|
What is the strongest chemo?
Doxorubicin (Adriamycin) is one of the most powerful chemotherapy drugs ever invented. It can kill cancer cells at every point in their life cycle, and it’s used to treat a wide variety of cancers.
Do you always lose your hair with docetaxel?
You usually lose all the hair from your head. You may also lose your eyelashes and eyebrows, as well as other body hair. Hair loss usually starts after your first or second treatment.
How many rounds of chemo can a person have?
Cycles are most often 3 or 4 weeks long, and initial treatment is typically 4 to 6 cycles. The schedule varies depending on the drugs used. For example, some drugs are given only on the first day of the chemo cycle. Others are given for a few days in a row, or once a week.
Does docetaxel cause heart problems?
However, since docetaxel induced the transient abnormalities of the serum BNP concentration, E:A ratio, and deceleration time, even in patients with normal cardiac function, it is possible that this agent may induce heart failure in patients with left ventricular dysfunction.
Is chemotherapy painful?
Does chemotherapy hurt? IV chemotherapy should not cause any pain while being administered. If you experience pain, contact the nurse taking care of you to check your IV line. An exception would be if there is a leak and the drug gets into surrounding tissues.
What does docetaxel therapy do?
What Docetaxel Is Used For: Approved in treatment of breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer and metastatic prostate cancer. Also being investigated to treat small cell lung, ovarian, bladder, and pancreatic cancers, soft tissue sarcoma and melanoma.